Global PECAM Antibody Market Top Leading Players with Strategies and Forecast 2022-2028

The global PECAM antibody market is anticipated to grow at a CAGR of 4.2% during the forecast period (2022-2028). Leukocytes and vascular endothelial cells both express platelet-endothelial cell adhesion molecule-1 (PECAM-1). In numerous animal models of acute inflammation, PECAM-1 has been demonstrated to play a key role in leukocyte transmigration. PECAM-1 has a key role in the advancement of CIA, suggesting that a PECAM-1 inhibitor could be useful in the therapy of rheumatoid arthritis. For instance, the anti-CD31/PECAM-1 antibody is a CD31/PECAM-1 antibody offered by Merck KGaA. Western blotting and flow cytometry applications use the CD31 antibody.

The role of platelet/endothelial cell adhesion molecule 1 (PECAM-1/CD31) in acute inflammation was investigated using a mouse model of peritonitis. For up to 48 hours, a mouse PECAM-1-specific monoclonal antibody (mAb) was given intravenously 4 hours before the intraperitoneal injection of thioglycollate broth inhibited leukocyte emigration into the peritoneal cavity. This was especially noticeable in neutrophils. When administered at the same or higher concentrations, control mAb, including one that linked to murine CD18 without disrupting its function, failed to stop emigration. The anti-PECAM-1 antibody did not cause neutropenia or neutrophil sequestration in the lungs, spleen, or other organs, and peripheral blood leukocyte levels were not affected in these animals. Leukocytes were commonly recognized in connection with the luminal surface of the artery in the mesenteric venules of mice treated with anti-PECAM-1 mAb but did not appear to emigrate. As a result, the necessity for PECAM-1 in leukocyte transendothelial migration in an in vitro model holds in an in vivo model of acute inflammation.

Some major players in the market include Abcam plc, BioLegend, Inc., Merck KGaA, Novus Biologicals, and Thermo Fisher Scientific Inc., among others. The market players are contributing significantly to the growth of the market by the adoption of various strategies including mergers and acquisitions, geographical expansion, partnerships, collaborations, and new product launches, to stay competitive in the market.

Antibodies that detect CD31 (PECAM-1) are available from Thermo Fisher Scientific Inc. They can be utilized in a variety of scientific applications, including Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunocytochemistry, and Immunohistochemistry (Frozen). In human, mouse, rat, non-human primate, and porcine samples, these antibodies target CD31 (PECAM-1). Mouse, Rabbit, Rat, and Armenian Hamster are used to generate monoclonal, polyclonal, and recombinant monoclonal antibodies against CD31 (PECAM-1). Relative expression and cell treatment were used to confirm specificity to CD31 in these antibodies (PECAM-1). Choose the CD31 (PECAM-1) antibody that best suits your requirements. There are 184 CD31 (PECAM-1) antibodies to choose from.

Market Coverage

• The market number available for – 2021-2028
• Base year- 2021
• Forecast period- 2022-2028
• Segment Covered-
  • By Type
  • By Application
• Regions Covered-
  • North America
  • Europe
  • Asia-Pacific
  • Rest of the World
• Competitive Landscape- Abcam plc., BioLegend, Inc., Merck KGaA, Novus Biologicals, Thermo Fisher Scientific Inc., among others.

Key questions addressed by the report

• What is the market growth rate?
• Which segment and region dominate the market in the base year?
• Which segment and region will project the fastest growth in the market?
• How has COVID-19 impacted the market?
  • Deviation from the pre-COVID-19 forecast
  • Most affected region and segment
• Who is the leader in the market?
• How players are addressing challenges to sustain growth?
• Where is the investment opportunity?

Global PECAM Antibody Market Report by Segment

By Application

• Western Blotting
• Flow Cytometry
• Immunocytochemistry (ICC)
• Immunohistochemistry (IHC)
• Other

Global PECAM Antibody Market Report by Region

North America

• United States
• Canada

Europe

• UK
• Germany
• Italy
• Spain
• France
• Rest of Europe

Asia-Pacific

• China
• India
• Japan
• South Korea
• Rest of Asia-Pacific

Rest of the World

• Latin America
• Middle East & Africa